Reports

Mutations: Incidence in Drosophila melanogaster Reared on Irradiated Medium

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Science  16 Aug 1963:
Vol. 141, Issue 3581, pp. 637-638
DOI: 10.1126/science.141.3581.637-a

Abstract

An increase in the rate of mutation has been found in Drosophila melanogaster reared on a basic medium that was irradiated with a sterilizing dose (150,000 rads) of cobalt-60 gamma rays. In Muller-5 tests, sex-linked recessive lethals occurred only in the F2 progenies of the male test flies obtained from breeding the parent flies on irradiated medium, while visible changes occurred in experimental cultures from both the control and irradiated media. The frequency of sex-linked recessive lethals was 0.35, 0.55, and 0.8 percent in three independent experiments. Visible changes were two to six times more frequent in the irradiated series than in the controls.