Cerebrally Active Small Moiety from "Taraxein-like" Blood Fractions

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Science  16 Aug 1963:
Vol. 141, Issue 3581, pp. 646-647
DOI: 10.1126/science.141.3581.646


A charged, amphoteric, smiall moiety has been separated from a "taraxein-like" blood fraction by electrodialysis throuighl ion exchange membranes. Cerebral bioassay shows that the activity of the blood extract is contained in the charged small moiety so that, as the activity in the charged compartment rises during electrodialysis, the activity in the feeding (extract) compartment falls.