Low Dose Radiation of the Developing Brain

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Science  06 Sep 1963:
Vol. 141, Issue 3584, pp. 903-905
DOI: 10.1126/science.141.3584.903


X-irradiation administered in single doses of 10 to 40 r has a widespread effect on the developing rat brain. It first diminishes the formation of cytoplasmic basophilic material in the nerve cells and inhibits their growth. Single doses of 20 to 40 r cause permanent alterations of individual nerve cells, and interfere with their organization into neuronal assemblies, such as layers of the cerebral cortex.