Circulating Small Lymphocytes: Immunologically Competent Cells with Limited Reactivities

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Science  27 Sep 1963:
Vol. 141, Issue 3587, pp. 1272-1274
DOI: 10.1126/science.141.3587.1272


Highly purified small lymphocytes from peripheral blood are capable of producing acute transplantation disease. However, such lymphocytes do not transfer from sensitized to normal mice the capacity to produce antibody to bovine serum albumin under conditions where mixed populations of lymphoid cells from the sensitized donors are effective.