Isolated Mammalian Eye: A Method for Quantitative Evaluation of Autonomic Drugs

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Science  27 Sep 1963:
Vol. 141, Issue 3587, pp. 1274-1275
DOI: 10.1126/science.141.3587.1274


The enucleated rodent eye can be mounted for study in vitro, in a chamber that contains electrodes suitably placed to enable the severed post-ganglionic nerves to the iris to be stimulated. The technique provides a simple quantitative method for the study of drugs which act at the parasympathetic neuro-effector junction.