Alcohol Consumption in Rats: Effects of Intracranial Injections of Ethanol

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Science  11 Oct 1963:
Vol. 142, Issue 3589, pp. 240-241
DOI: 10.1126/science.142.3589.240


After permanent implantation of intraventricular cannulae, rats were repeatedly infused with ethanol solutions of several concentrations. Pro-nounced preferences were exhibited for ordinarily noxious ethanol without prior oral exposure to this fluid. Since preferences for ethanol remained unusually high after cessation of infusion, a permanent change may take place in the central nervous system. central nervous system.