Ornithocholanic Acids and Cholelithiasis in Man

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Science  11 Oct 1963:
Vol. 142, Issue 3589, pp. 245-246
DOI: 10.1126/science.142.3589.245


Ornithocholanic acids and small soft gall stones were found in the bile of patients from which Klebsiella pneumoniae was also isolated. Cholelithiasis may be initiated by metabolic disturbances in the conjugation of bile acids in liver tissue and the subsequent precipitation of cholesterol and bile pigment.