Coliagenolytic Activity in Mammalian Bone

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Science  18 Oct 1963:
Vol. 142, Issue 3590, pp. 386-387
DOI: 10.1126/science.142.3590.386


Collagen from bone was incubated with bone-cell homogenate. At the end of incubation the collagen had been partially broken down to ultrafiltrable units indicating that ferments with collagenolytic activity, which can be released by homogenization, exist in bone cells.