Canine Antiserums Analogous to Human Allergic and "Blocking" Antiserums

Science  01 Nov 1963:
Vol. 142, Issue 3592, pp. 589-590
DOI: 10.1126/science.142.3592.589


The serums of dogs that are allergic to ragweeed can passively sensitize normal dogs. Cutaneous reactions or systemic anaphylaxis may be produced by appropriate challenge with ragweed extract. Canine antiserum produced by immunization of normal dogs with ragweed extract is shown to inhibit these reactions of the passively sensitized dogs.