Aflatoxin B2: Chemical Identity and Biological Activity

Science  29 Nov 1963:
Vol. 142, Issue 3596, pp. 1191-1192
DOI: 10.1126/science.142.3596.1191


Aflatoxin B2, a blue-fluorescent metabolite of Aspergillus flavus, was isolated from cultures grown on crushed wheat. Chemical structure of the compound was elucidated as dihydroaflatoxin B1. Biological activity was determined in day-old male white Pekin ducklings. The criteria of activity were reduction in growth and liver size and the extent of bile-duct hyperplasia.