Tautomerism and Protonation of Guanosine

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Science  13 Dec 1963:
Vol. 142, Issue 3598, pp. 1458-1463
DOI: 10.1126/science.142.3598.1458


Guanosine has been demonstrated, by infrared and nuclear magnetic resonance spectroscopy, to have a keto-amino structure in neutral aqueous solution and to undergo protonation at N7 in acid solution.