Actinomycin D: Its Effect on Antibody Formation in vitro

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Science  13 Dec 1963:
Vol. 142, Issue 3598, pp. 1476-1477
DOI: 10.1126/science.142.3598.1476


The formation of antibodies to bacteriophage T2 in vitro was inhibited by 5 X 10-8M actinomycin D. This result is consistent with the concept that antibody formation depends upon DNA-dependent RNA synthesis.