Serum Factor in Renal Compensatory Hyperplasia

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Science  13 Dec 1963:
Vol. 142, Issue 3598, pp. 1479-1480
DOI: 10.1126/science.142.3598.1479


Serum from uninephrectomized rats was injected into normal recipient rats. This led to an increased incorporation of tritiated thymidine in the kidney cells, but not in the liver cells of the recipients. The results suggest that there is a humoral substance acting specifically on the kidney that promotes renal compensatory hyperplasia.