Toxohormone Inhibitory Effect on the Growth of an Unstable Strain of Yeast

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Science  27 Dec 1963:
Vol. 142, Issue 3600, pp. 1668-1669
DOI: 10.1126/science.142.3600.1668


Toxohormone preparations obtained from yeast mutants with impaired respiration and from cancerous tissues inhibited the growth of an unstable strain of yeast in media containing lactate as the carbon source. Depending on the source of the different toxohormone preparations, amounts ranging from 5 to 9.5 mg/ml inhibited growth by 50 percent. This phenomenon could be utilized in quantitative evaluations of toxohormone activity.