Oncogenic Effect of Human Adenovirus Type 12, in Mice

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Science  03 Jan 1964:
Vol. 143, Issue 3601, pp. 46-47
DOI: 10.1126/science.143.3601.46


Undifferentiated malignant tumors were induced at the site of injection of human adenovirus type 12 into newborn mice of the C3Hf/ G8. strain, but not of the DBAf, or Af strains. The tumors were grossly and histologically similar to those induced by this virus in hamsters, but appeared in a smaller percentage of injected mice than hamsters.