Identity of Tarichatoxin and Tetrodotoxin

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Science  31 Jan 1964:
Vol. 143, Issue 3605, pp. 474-475
DOI: 10.1126/science.143.3605.474


Tarichatoxin (C11H17N3O8), a potent neurotoxin recently isolated in pure form from the eggs of the California newt, Taricha torosa, has been found to be identical to tetrodotoxin from the ovaries of Sphoeroides rubripes, the Japanese Fugu or puffer fish. As yet this substance has been detected only in a single family of fish, Tetraodontidae, and in a single family of amphibia, Salamandridae.