Reports

Allelic Mapping in Yeast by X-ray-Induced Mitotic Reversion

See allHide authors and affiliations

Science  07 Feb 1964:
Vol. 143, Issue 3606, pp. 581-582
DOI: 10.1126/science.143.3606.581

Abstract

A new method for determining the sequence of mutational sites is based on the linear dose-effect relation for x-ray induction of allelic recombination in Saccharomyces cerevisiae. Mutations at two loci have been mapped by this method. The use of x-ray simplifies allelic mapping and greatly increases its sensitivity.