Hemoglobin Gcoushatta: A New Variant in an American Indian Family

Science  14 Feb 1964:
Vol. 143, Issue 3607, pp. 697-698
DOI: 10.1126/science.143.3607.697


A new hemoglobin variant, Gcouhatta (α2A β2iiiglu→ala), has been found in three generations of a family from the Alabama Coushatta Indian tribe in east Texas. The propositus suffers from an apparently unrelated, possibly genetic, agranulocytosis. According to the history and the blood grouping data there is considerable in breeding in the tribe and remarkably little admixture with other ethnic groups.