Intercellular Diffusion

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Science  28 Feb 1964:
Vol. 143, Issue 3609, pp. 959-960
DOI: 10.1126/science.143.3609.959


Fluorescein-sodium, a fluorescent tracer whose molecular weight is 376, diffuses rather freely from the interior of one cell to another in a gland epithelium (Drosophila) but does not diffuse along the intercellular space to the exterior. The permeability of the junctional surfaces of the cell membranes appears to be high, in contrast to the nonjunctional surfaces and intercellular spaces which represent strong diffusion barriers.