Inheritance of Avoidance Conditioning in Mice: A Diallel Study

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Science  13 Mar 1964:
Vol. 143, Issue 3611, pp. 1188-1190
DOI: 10.1126/science.143.3611.1188


Significant genetic differences were demonstrated in the rate of avoidance conditioning among offspring from all 25 mating combinations of 5 highly inbred mouse strains. Hybrids of C3H parents learned fastest, while those of A/JAX parents learned slowest. Most hybrids learned better than either parent. Evidence that differential influences of the early maternal environment affected the rate of learning was not supported.