Giant Polytene Chromosomes in Hypodermal Cells of Developing Footpads of Dipteran Pupae

Science  27 Mar 1964:
Vol. 143, Issue 3613, pp. 1437-1438
DOI: 10.1126/science.143.3613.1437


Large hypodermal cells with giant polytene chromosomes are present within the developing feet of Sarcophaga and other fly pupae. The cells secrete a large volume of cuticle; at this time there is extensive "puffing" of the chromosomes. Being hypodermal and superficially situated with permanent secretory products, the cells could be ideal experimental and genetical tools.