Chromosome Number and Morphology of a Human Preinvasive Neoplasm

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Science  03 Apr 1964:
Vol. 144, Issue 3614, pp. 65-67
DOI: 10.1126/science.144.3614.65


The cervical epithelium from five patients with varying degrees of histologically proven intra-epithelial neoplasia can be grown successfully in tissue culture. After four or less successive transfers, the cells are diploid and have a normal karyotype.