Audiogenic Seizures, the Dilute Locus, and Phenylalanine Hydroxylase in DBA/1 Mice

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Science  17 Apr 1964:
Vol. 144, Issue 3616, pp. 304-305
DOI: 10.1126/science.144.3616.304


Reduced audiogenic seizure susceptibility in dilute mice was associated with enhancement of phenylalanine hydroxylase activity, previously reported as low in dilute mice. Though nutritional changes complicate the interpretation, evidence exists for a mutation linked with dilute which modifies susceptibility.