Effect of Bromination on the Biological Activities of Transfer RNA of Escherichia coli

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Science  15 May 1964:
Vol. 144, Issue 3620, pp. 856-859
DOI: 10.1126/science.144.3620.856


A transfer RNA molecule accepts a particular amino acid from an activating enzyme and subsequently transfers it to the end of a growing peptide chain, in association with ribosomes and messenger RNA. The acceptor and transfer functions of transfer RNA differ in their sensitivity to damage by bromination, and thus appear to comprise different areas on the transfer RNA molecule.