Antibodies to Bradykinin and Angiotensin: A Use of Carbodiimides in Immunology

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Science  12 Jun 1964:
Vol. 144, Issue 3624, pp. 1344-1346
DOI: 10.1126/science.144.3624.1344


Antibodies to bradykinin and angiotensin have been produced in rabbits by the use of conjugates containing albumin and the hapten, covalently bound. The use of water-soluble carbodiimide reagents provided an easy and rapid method of synthesis of the antigenic conjugates.