Phenoloxidase System of the Blowfly, Calliphora erythrocephala

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Science  03 Jul 1964:
Vol. 145, Issue 3627, pp. 68-69
DOI: 10.1126/science.145.3627.68


In Calliphora larvae, an inactive precursor of the enzyme phenoloxidase is present in the hemolymph. A special activator enzyme is localized in the cuticle. When phenoloxidase precursor is allowed to react with the activator, it yields a soluble enzyme having the characteristics mainly of a diphenoloxidase. If, however, this conversion takes place in the presence of mitochondria, the phenoloxidase becomes bound to the mitochondria and the resulting preparation shows equally mono- and diphenoloxidase activity.