Genetics of Isoniazid Metabolism in Caucasian, Negro, and Japanese Populations

Science  24 Jul 1964:
Vol. 145, Issue 3630, pp. 391
DOI: 10.1126/science.145.3630.391


Trimodal frequency distributions for isoniazid inactivation were found in Caucasian and Negro populations. The frequency of "rapid" and "slow" alleles in Caucasian and Negro populations was similar and differed from that of a Japanese population.