Allotypic Specificities of A- and B- Chains of Rabbit Gamma Globulin

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Science  24 Jul 1964:
Vol. 145, Issue 3630, pp. 403-405
DOI: 10.1126/science.145.3630.403


The extent to which the A-chain of γ-globulin reacted with antibody against an allotypic specificity controlled by the b locus was about that expected from the contamination of A-chain with B-chain; the a locus specificity was confined only to A-chain. Thus, data were consistent with complete separation of allotypic specificities, a locus with A-chain and b locus with B-chain.