Polyploidy Induced by X-rays in Chinese Hamster Cells in vitro

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Science  31 Jul 1964:
Vol. 145, Issue 3631, pp. 508-510
DOI: 10.1126/science.145.3631.508


The incidence of polyploidy (specifically, in this case, the doubling of the stemline chromosome number) induced by x-rays in cells cultured in vitro is about the same for both "near-diploid" and "near-tetraploid" sublines of the Chinese hamster. Endoreduplication is a principal cytological mechanism for this form of induced polyploidy.