Host Cell Species Specificity of Mouse and Chicken Interferons

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Science  21 Aug 1964:
Vol. 145, Issue 3634, pp. 814
DOI: 10.1126/science.145.3634.814


Three thousand units of mouse interferon and 2000 units of chicken interferon were assayed on the respective heterologous species cell cultures. No antiviral activity was observed in the heterologous systems, suggesting a virtually complete species barrier to the action of these interferons