Macroglobulin from Human Plasma Which Forms an Enzymaticaliy Active Compound with Trypsin

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Science  21 Aug 1964:
Vol. 145, Issue 3634, pp. 821-822
DOI: 10.1126/science.145.3634.821


The protein from human plasma which forms an enzymatically active complex with trypsin and is able to protect trypsin from inhibition by soybean trypsin inhibitor has been shown to be an α2-macroglobulin. It was obtained from the lipid-poor euglobulin of Cohn Fraction III-0, and appears to be closely related to the 19S-glycoprotein or α2macroglobulin