Thymus: Role in Maturation of Fetal Lymphoid Precursors

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Science  28 Aug 1964:
Vol. 145, Issue 3635, pp. 934-935
DOI: 10.1126/science.145.3635.934


Liver cells from homozygous embryonic mice were subjected to serial passage through appropriate thymectomized and sham-thymectomized F1 hybrids. Passage through a nonthymectomized host was required for maturation and/or proliferation of the potential immunologically competent cells in the embryonic liver