Antigenic Behavior of Moloney Lymphomas: Independence of Virus Release and Imunosensitivity

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Science  18 Sep 1964:
Vol. 145, Issue 3638, pp. 1316-1317
DOI: 10.1126/science.145.3638.1316


Mouse lymphomas induced by Moloney virus were compared with regard to their ability to elicit humoral antibodies against Moloney cells, to sensitize against Moloney isografts, and to respond to established isograft resistance. The first two properties were parallel, while the third was independent. The former, but not the latter, is attributed to the release of infectious virus.