Specific Inhibition of Antibody Formation by Passively Administered 19S and 7S Antibody

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Science  02 Oct 1964:
Vol. 146, Issue 3640, pp. 67-69
DOI: 10.1126/science.146.3640.67


Intravenously administered 7S antibody is more effective than 19S antibody in inhibiting the formation of antibody to bacteriophage ϕX174. Since considerable amounts of 7S antibody are needed for inhibition, serum antibody formation may act as a "feedback" mechanism to prevent hyperimmunization.