Reports

Ostracitoxin: An Ichthyotoxic Stress Secretion of the Boxfish, Ostracion lentiginosus

Science  09 Oct 1964:
Vol. 146, Issue 3641, pp. 244-245
DOI: 10.1126/science.146.3641.244

Abstract

Boxfish under stress produce an ichthyotoxic, hemolytic, nonprotein poison in the mucous secretions of their skin. This heat-stable, nondialyzable "ostracitoxin" foams profusely in aqueous solutions and is toxic to various biological systems. It is apparently unique among known fish poisons; it is toxic to boxfish and resembles red tide and sea cucumber toxins in general properties.