Reports

Crystal and Molecular Structure of Ferrichrome A

Science  09 Oct 1964:
Vol. 146, Issue 3641, pp. 261-263
DOI: 10.1126/science.146.3641.261

Abstract

The crystal structure of ferrichrome A (C41H58N9O20Fe·4H2O) has been determined by x-ray diffraction. The amino acid sequence in the hexapeptide ring is confirmed to be -Orn-Orn-Orn-Ser-Ser-Gly-, and the conformation of this ring is trans at each peptide linkage. The absolute configuration of the three hydroxamate rings at the iron atom is that of a left-handed propeller. Disorder is found concerning the positions of some of the side chains and one of the four water molecules.

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