Thyrocalcitonin: Hypocalcemic Hypophosphatemic Principle of the Thyroid Gland

Science  16 Oct 1964:
Vol. 146, Issue 3642, pp. 412-413
DOI: 10.1126/science.146.3642.412


A factor that lowers serum calcium and inorganic phosphate in rats has been purified 500-fold from 0.1N HCl extracts of hog thyroid glands. It is distinct from thyroxine and triiodothyronine and appears to be a polypeptide.