Semipermeable Microcapsules

Science  23 Oct 1964:
Vol. 146, Issue 3643, pp. 524-525
DOI: 10.1126/science.146.3643.524


Simple methods have been developed for encapsulating aqueous solutions of protein within polymer membranes. Stable microcapsules 1 to 100 µ in diameter, with semipermeable membranes, can be made by depositing polymer around emulsified aqueous droplets, either by interfacial coacervation or by interfacial polycondensation. Aqueous suspensions of enzyme-loaded microcapsules act well on small-molecular substrates both in vitro and in vivo.