Human Wart Virus: In vitro Cultivation

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Science  23 Oct 1964:
Vol. 146, Issue 3643, pp. 531-533
DOI: 10.1126/science.146.3643.531


Inoculation of cell cultures of fetal skin of human and murine origin with virus extracted from human wart tissue resulted in the appearance of intracellular wart virus specific antigen, as demonstrated by fluorescent antibody techniques. Appearance of antigen was accompanied by cytopathogenicity and the accumulation of large numbers of characteristic virus particles.