Human Blood Group A1 Specific Agglutinin of the Butter Clam Saxidomus giganteus

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Science  23 Oct 1964:
Vol. 146, Issue 3643, pp. 548-549
DOI: 10.1126/science.146.3643.548


Saline extracts of the butter clam Saxidomus giganteus specifically agglutinated human red blood cells of phenotypes A1 and A1B. The agglutinin was completely absorbed by A1 and A1B cells, partially absorbed by A2 cells, and unaffected by B and O cells. Of 21 sugars tested, only N-acetyl-d-galactoseamine and N-acetyl-d-glucoseamine inhibited the agglutinin.