Spreading Depression and Recovery from Lateral Hypothalamic Damage

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Science  01 Jan 1965:
Vol. 147, Issue 3653, pp. 61-63
DOI: 10.1126/science.147.3653.61


Spreading cortical depression reinstates aphagia and adipsia in rats recovered from lateral hypothalamic lesions. We suggest that cortical activity facilitates and maintains recovery by enhancing the activity of depressed, but intact, tissue adjacent to the lesions.