Exovagination of Newt Endoderm: Cell Affinities Altered by the Mesodermal Inducing Factor

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Science  08 Jan 1965:
Vol. 147, Issue 3654, pp. 167-169
DOI: 10.1126/science.147.3654.167


Implantation of a highly purified mesodermal inducing factor in the blastocoel of early gastrulae results in the spreading of endoderm over the ectoderm. The effect can be explained by a change in cell affinities in the ectoderm, initiated by the mesodermal factor.