Simian Virus 40: Isolation of Two Plaque Types

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Science  22 Jan 1965:
Vol. 147, Issue 3656, pp. 408-409
DOI: 10.1126/science.147.3656.408


Two different morphological plaque types of simian virus 40 were isolated from three of six strains. Increased uptake of neutral red gave one type of plaque a uniform red appearance, whereas the center of the other remained unstained. The viruses showed stability of plaque morphology on passage in tissue culture; cross neutralization studies identified both as simian virus 40.