Complement: Inactivation of Second Component by p-Hydroxymercuribenzoate

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Science  26 Feb 1965:
Vol. 147, Issue 3661, pp. 1034-1035
DOI: 10.1126/science.147.3661.1034


p-Hydroxymercuribenzoate inactivates the second component of complement whether it is in solution or is fixed to a sensitized erythrocyte together with the first and fourth components. Inactivation by the drug is blocked but not reversed by cysteine. Partial purification of the second component of complement is described.