Cholesterol Biosynthesis: Mevalonate Synthesis Inhibited by Bile Salts

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Science  26 Feb 1965:
Vol. 147, Issue 3661, pp. 1038
DOI: 10.1126/science.147.3661.1038


Certain bile salts inhibit biosynthesis of mevalonate from acetate-2-C14 in normal rat liver homogenates. The physiological control of cholesterol biosynthesis is discussed.

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