Iron Accumulation in Cockerel Plasma after Estrogen: Relation to Induced Phosphoprotein Synthesis

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Science  26 Mar 1965:
Vol. 147, Issue 3665, pp. 1571-1572
DOI: 10.1126/science.147.3665.1571-a


In cockerels a single injection of estrogen causes a rise of several fold in the plasma iron. At 18 hours this response is proportional to the amount of diethylstilbestrol injected and may be used as a convenient measure of estrogen action. The phenomenon is probably related to the estrogen-induced synthesis of iron-binding phosphoproteins.