Ciguatera Fish Poison: A Cholinesterase Inhibitor

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Science  26 Mar 1965:
Vol. 147, Issue 3665, pp. 1580-1581
DOI: 10.1126/science.147.3665.1580


The substance responsible for the poisoning effect of ciguatera poison from fish is an anticholinesterase. In rats, mice, and rabbits ciguatera poison causes death by asphyxiation. Protopam chloride with atropine is an effective antidote.