Reports

Tricarboxylic Acid Cycle Mutants in Saccharomyces: Comparison of Independently Derived Mutants

+ See all authors and affiliations

Science  26 Mar 1965:
Vol. 147, Issue 3665, pp. 1590
DOI: 10.1126/science.147.3665.1590

Abstract

A yeast mutant independently isolated as a glutamate auxotroph (glt2-1) was similar to the glt1-1 mutant in exhibiting a blocked tricarboxylic acid cycle due to the lack of aconitate hydratase. The new mutant differed by exhibiting blocks in lysine and cytochrome biosynthesis which segregated together with the glutamate requirement.

Related Content