Sex Chromatin in Newborns: Presumptive Evidence for External Factors in Human Nondisjunction

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Science  02 Apr 1965:
Vol. 148, Issue 3666, pp. 83-85
DOI: 10.1126/science.148.3666.83


An incidence of 0.6 percent of sex-chromosome aberrations in newborns was found during a 5-month period, while no aberrations occurred in similar populations before and after this period. Down's syndrome also exhibited an elevated frequency during this same critical interval. A severe rubella epidemic may have influenced this pattern.