Culture of Dissociated Drosophila Embryos: Aggregated Cells Differentiate and Sort Out

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Science  23 Apr 1965:
Vol. 148, Issue 3669, pp. 502-503
DOI: 10.1126/science.148.3669.502


When the cells of Drosophila embryos are dissociated and cultured in vitro, aggregation of the cells begins rapidly and movements of the cells continue for at least 5 days. Oenocytes, hypoderm, nerve, muscle, and trachea cells take up characteristic positions in the aggregates. Cells from X2 mutant embryos sort out in identically the same way as do cells from normal embryos.